Thomas Grochow

Thomas Grochow

Research Fellow

Funktionelle Histologie und Embryologie
Anatomie, Tierhygiene
An den Tierkliniken 41-43
04103 Leipzig

Phone: +49 341 97-38084

Abstract

Research associate and doctoral student at the Institute of Veterinary Anatomy and Institute of Parasitology


PreDoc Award 2017 University of Leipzig

Best scientific poster, Doktorandenforum 2020, University of Leipzig

Thomas Schnieder Young Scientist Award for the best scientific presentation, DVG Conference Parasitology, Munich 2021

Professional career

  • 11/2013 - 07/2015
    Student assistant at the Institute of Veterinary Anatomy, department of histology, University of Leipzig
  • 10/2015 - 03/2016
    Lecturer at the Institute of Veterinary Anatomy, department of histology, University of Leipzig

Education

  • 10/2011 - 02/2017
    Studied veterinary medicine at the University of Leipzig
  • since 07/2017
    Doctoral student at the Institute of Veterinary Anatomy and Institute of Parasitology, University of Leipzig

Establishment and Validation of a Guinea Pig Model for Human Congenital Toxoplasmosis

Prof. Fietz, Simone and Prof. Daugschies, Arwid

Running time: 07/2017- 03/2020

Funding: German Research Platform for Zoonoses, BMBF



Toxoplasmosis is one of the most widespread zoonoses worldwide. It is caused by the unicellular parasite Toxoplasma gondii. Among other things, this parasite has a pronounced tropism for neuronal cells. The main host of the parasite is the cat, whose faeces or raw consumption of infected intermediate hosts can infect humans. If the mother is infected for the first time during pregnancy, the foetuses are infected vertically, often resulting in extensive neural malformations or abortion.


To date, no data exist on the exact cell tropism of T. gondii during brain development.


The aim of this project is to establish the guinea pig as a model animal for congenital toxoplasmosis, in particular for human congenital toxoplasmosis, and to validate pathomorphological and immunohistological findings based on pathogen transmission. The project provides the basis for the use of the guinea pig as an animal model for the investigation of scientific questions of high topicality and clinical importance, including the pathogenesis, diagnosis, therapy and prognosis of congenital toxoplasmosis.

  • Cell tropism of Toxoplasma gondii in the adult brain of mouse and chicken
    Fietz, Simone
    Duration: 01/2017 - ongoing
    Funded by: BMBF Bundesministerium für Bildung und Forschung
    Involved organisational units of Leipzig University: Veterinär-Anatomisches Institut
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more projects

  • Beck, B.; Grochow, T.; Schares, G.; Blaga, R.; Le Roux, D.; Daugschies, A.; Fietz, S.
    Burden and regional distribution of Toxoplasma gondii cysts in the brain of COBB 500 broiler chickens following chronic infection with 76K strain
    Veterinary Parasitology. 2021.
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more publications