Research associate and doctoral student at the Institute of Veterinary Anatomy and Institute of Parasitology
PreDoc Award 2017 University of Leipzig
Best scientific poster, Doktorandenforum 2020, University of Leipzig
Thomas Schnieder Young Scientist Award for the best scientific presentation, DVG Conference Parasitology, Munich 2021
- 11/2013 - 07/2015
Student assistant at the Institute of Veterinary Anatomy, department of histology, University of Leipzig
- 10/2015 - 03/2016
Lecturer at the Institute of Veterinary Anatomy, department of histology, University of Leipzig
- 10/2011 - 02/2017
Studied veterinary medicine at the University of Leipzig
- since 07/2017
Doctoral student at the Institute of Veterinary Anatomy and Institute of Parasitology, University of Leipzig
Establishment and Validation of a Guinea Pig Model for Human Congenital Toxoplasmosis
Prof. Fietz, Simone and Prof. Daugschies, Arwid
Running time: 07/2017- 03/2020
Funding: German Research Platform for Zoonoses, BMBF
Toxoplasmosis is one of the most widespread zoonoses worldwide. It is caused by the unicellular parasite Toxoplasma gondii. Among other things, this parasite has a pronounced tropism for neuronal cells. The main host of the parasite is the cat, whose faeces or raw consumption of infected intermediate hosts can infect humans. If the mother is infected for the first time during pregnancy, the foetuses are infected vertically, often resulting in extensive neural malformations or abortion.
To date, no data exist on the exact cell tropism of T. gondii during brain development.
The aim of this project is to establish the guinea pig as a model animal for congenital toxoplasmosis, in particular for human congenital toxoplasmosis, and to validate pathomorphological and immunohistological findings based on pathogen transmission. The project provides the basis for the use of the guinea pig as an animal model for the investigation of scientific questions of high topicality and clinical importance, including the pathogenesis, diagnosis, therapy and prognosis of congenital toxoplasmosis.
- Cell tropism of Toxoplasma gondii in the adult brain of mouse and chickenFietz, SimoneDuration: 01/2017 - ongoingFunded by: BMBF Bundesministerium für Bildung und ForschungInvolved organisational units of Leipzig University: Veterinär-Anatomisches Institut