The host is constantly exposed to attack by pathogens. In the focus blood and defense in the 3rd semester aspects of the pathogen defense are mediated and how pathogens manage to outwit the immune system by evasion mechanisms.

The focus on blood and defence is on immunological aspects of defence against pathogens. Photo: Colourbox

Focus Blood and Defense

The focus Blood and Defense deals with the aspects of pathogen-host interactions. Students learn in 18 lectures about selected interactions between the pathogen and the host, the immune responses of the host and the evasion mechanisms of the pathogen.

  • blood, haematopoiesis
  • erythrocytes
  • bleeding protection
  • Primary lymphatic organs
  • Secondary lymphatic organs
  • Function of leukocytes in the innate immune defence (1)
  • Function of leukocytes in the innate immune defence (2)
  • Function of leukocytes in adaptive immune defence: cellular immunity
  • Function of leukocytes in adaptive immune defence: humoral immunity
  • Function of leukocytes in adaptive immune defence: antibodies
  • Blood count in clinical diagnostics
  • Blood group antigens, blood transfusion reactions
  • Immunopathological examples (blood)
  • Diagnostic examples (blood)

Blood composition, blood groups, blood group incompatibilities

  • definition can reflect blood group
  • Being able to explain test systems for blood group compatibility
  • the development of neonatal isoerythrolysis in horses can be described

maturation of immune cells in primary lymphatic organs

  • be able to describe the selection processes of T/B cells in the primary lymphatic organs

Activation of immune cells in secondary lymphatic organs

  • be able to explain the activation of T/B cells in secondary lymphatic organs
  • be able to describe the circulation of immune cells in the body

Basics of innate immunity

  • be able to explain the modes of action of innate immunity (complement, phagocytosis, left shift, antigen presentation, chemotaxis)

Basics of T cell immunity

  • be able to describe the activation of T cells by APC after pathogen contact

Basics of antibody structure and mechanisms of action

  • be able to reproduce the structure and mechanisms mediated by antibodies and antibodies (opsonization, complement activation, neutralization, ADCC)
  • can name the antibody isotypes

Basics of B-cell immunity

  • Being able to explain the development of antibody diversity as well as mechanisms of clonal selection, affinity maturation and class change
  • be able to demonstrate the importance of immunological memory for vaccination success

In addition, employees of the Institute of Immunology are involved in the organization of various focus events.

The Institute of Immunology is responsible for focus events marked with *. As soon as the other focus events are listed on the websites of the responsible institutes and clinics, links will take you to the respective focus events.

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